Vetenskapliga Publikationer

 

Alexandre J, Nicco C, Chéreau C, Laurent A, Weill B, Goldwasser F & Batteux F: Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir. J Natl Cancer Inst 2006;98:236-244.

Andre T, Boni C, Mounedji-Boudiaf L, Matilde Navarro, Josep Tabernero, Tamas Hickish, et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 2004;350:2343-2351.

Asplund A, Grant D & Karlsson JOG: MnDPDP- and MnCl2-induced endothelium-dependent relaxation in bovine mesenteric arteries: J Pharmacol Exp Ther 1994;271:609-614.

Bedda S, Laurent A, Conti F, Chéreau C, Tran A, Tran-Van Nhieu J, Jaffray P, Soubrane O, Goulvestre C, Calmus Y, Weill B & Batteux F: Mangafodipir prevents liver injury induced by acetaminophen in the mouse. J Hepatol 2003;39:765-772.

Brurok H, Ardenskjær-Larsen JH, Hansson G, Skarra S, Berg K, Karlsson JOG, Laursen I & Jynge P: Manganese dipyridoxyl diphosphate: MRI contrast agent with antioxidative and cardioprotective properties? In vitro and ex vivo assessments. Biochem Biophys Res Commun 1999;254:768-772.

Culotta VC, Yang M & O’Halloran TV. Activation of superoxide dismutases: putting the metal to the pedal. Biochim Biophys Acta 2006;1763:747-758.

Cuzzocrea S, Riley DP, Caputi AP & Salvemini D. Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol Rev 2001;53:135-159.

Doroshow JH: Editorial: Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity. J Natl Cancer Inst 2006;98:223-225.

Fridovich, I. Oxygen toxicity: a radical explanation. J Exp Biol 1998;201:1203-1209.

Hausenloy DJ, Yellon DM. Time to take myocardial reperfusion injury seriously. N Engl J Med. 2008;359:518-520.

Jynge P, Brurok H, Asplund A, Towart R & Karlsson JOG: Cardiovascular safety of MnDPDP and MnCl2. Acta Radiol 1997;38:740-749.

Karlsson JO, Adolfsson K, Thelin B, Jynge P, Andersson RG, Falkmer UG. First clinical experience with the magnetic resonance imaging contrast agent and superoxide dismutase mimetic mangafodipir as an adjunct in cancer chemotherapy – a translational study. Transl Oncol. 2012;5:32-38.

Karlsson JOG. Antioxidant activity of mangafodipir is not a new finding. J Hepatol 2004;40:872-873.

Karlsson JOG, Brurok H, Eriksen M, Towart R, Toft KG, Moen O, Engebretsen B, Jynge P & Refsum H: Cardioprotective effects of the MR contrast agent MnDPDP and its metabolite MnPLED upon reperfusion of the ischemic porcine myocardium. Acta Radiol 2001;42:540-547.

Karlsson JOG, Brurok H, Towart R & Jynge P: The MRI contrast agent mangafodipir exerts anti-tumour activity via a previously described SOD mimetic activity. Cancer Res 2006;66:598.

Laurent A, Nicco C, Chéreau C, Goulvestre C, Alexandre J, Alves A, Lévy E, Goldwasser F, Panis Y, Soubrane O, Weill B & Batteux F: Controlling tumor growth by modulating endogenous production of reactive oxygen species. Cancer Res 2005;65:948-956.

McCord JM & Fridovich I: Superoxide dismutase: an enzymatic function for erythrocuprein (hemocuprein). J Biol Chem 1969;244:6049-6055.

O’Neil BH & Goldberg RM. Innovations in chemotherapy for metastatic colorectal cancer: an update of recent clinical trials. Oncologist. 2008;13:1074-1083.

Piot C, Croisille P, Staat P, Thibault H, Rioufol G, Mewton N, Elbelghiti R, Cung TT, Bonnefoy E, Angoulvant D, Macia C, Raczka F, Sportouch C, Gahide G, Finet G, André-Fouët X, Revel D, Kirkorian G, Monassier JP, Derumeaux G, Ovize M. Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med. 2008;359:473-481.

Rocklage SM, Cacheris WP, Steven C. Quay,F. Hahn FE & Raymond KN. Manganese (II) N,N’-dipyridoxylethylenediamine-N,N’-diacetate 5,5’-bis(phosphate). Synthesis and characterization of a paramagnetic chelate for magnetic resonance imaging enhancement. Inorg Chem 1989; 28:477-485.

Smith H-J: Editorial: Contrast-enhanced MR imaging in the diagnosis and preservation of cardiac viability. Acta Radiol 42, 539, 2001.

Towart R, Jynge P, Refsum H & Karlsson JOG: Manganese dipyridoxyl diphosphate protects against acute anthracycline induced cardiotoxicity mice. Arch Pharmacol 1998:358(Suppl 2): R626.

Towart R, Refsum H, Sager G, Toft K & Karlsson JOG: Cardiovascular safety of intravenously administered MnDPDP as compared with MnCl2 in the conscious beagle dog. Br J Pharmacol 1997;120 (suppl):158.

Yri OE, Vig J, Hegstad E, Hovde O, Pignon I, Jynge P. Mangafodipir as a cytoprotective adjunct to chemotherapy – a case report. Acta Oncol. 2009;48:633-635.